The Pan-American Journal of Ophthalmology

CASE REPORT
Year
: 2023  |  Volume : 5  |  Issue : 1  |  Page : 27-

Tubulointerstitial nephritis with uveitis in a young male patient


Juan Jose Castro-Barandica1, Daniela A Esmeral-Ordonez1, Karol Quintero-Lizcano1, Carlos Mario Rangel2 
1 Autonomous University of Bucaramanga, Bucaramanga; Virgilio Galvis Ophthalmological Center; Ophthalmologic Foundation of Santander, Floridablanca, Santander, Colombia
2 Autonomous University of Bucaramanga, Bucaramanga; Virgilio Galvis Ophthalmological Center; Ophthalmologic Foundation of Santander, Floridablanca, Santander; Industrial University of Santander, Bucaramanga, Colombia

Correspondence Address:
Juan Jose Castro-Barandica
Centro Oftalmológico Virgilio Galvis, FOSCAL Internacional, Calle 157#20 – 94, Torre C, Consultorio 301, Cañaveral, Floridablanca, Santander
Colombia

Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare inflammatory disorder affecting renal and ocular systems. Certain associations have been made with systemic conditions such as autoimmune diseases, infections, and even medications. We present the case of a 16-year-old male patient who presented to our service with bilateral uveitis and urinary symptoms, associated with proteinuria, glycosuria, increase in serum creatinine and beta-2 microglobulin in urine considering TINU as the main differential diagnosis. Antibiotics were considered a possible trigger in this patient. He presented an adequate response to systemic and topical steroids and systemic immunomodulators. Renal biopsy results reported interstitial tubulonephritis. TINU syndrome is a rare autoimmune condition, mainly seen in younger patients. Multiple triggers have been associated. Renal compromise usually resolves spontaneously with a relatively rare risk of incomplete recovery as well as uveal compromise. However, early diagnosis and multidisciplinary management is fundamental in these patients.


How to cite this article:
Castro-Barandica JJ, Esmeral-Ordonez DA, Quintero-Lizcano K, Rangel CM. Tubulointerstitial nephritis with uveitis in a young male patient.Pan Am J Ophthalmol 2023;5:27-27


How to cite this URL:
Castro-Barandica JJ, Esmeral-Ordonez DA, Quintero-Lizcano K, Rangel CM. Tubulointerstitial nephritis with uveitis in a young male patient. Pan Am J Ophthalmol [serial online] 2023 [cited 2023 Sep 29 ];5:27-27
Available from: https://www.thepajo.org/article.asp?issn=2666-4909;year=2023;volume=5;issue=1;spage=27;epage=27;aulast=Castro-Barandica;type=0