ORIGINAL ARTICLE
Year : 2023 | Volume
: 5 | Issue : 1 | Page : 10-
Optical coherence tomography biomarkers after intravitreal triamcinolone acetonide in patients with diabetic macular edema
Maria João Matias, Vítor Miranda, Catarina Pestana Aguiar, Lilianne Duarte
Department of Ophtalmology of the Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, Portugal
Correspondence Address:
Maria João Matias
Department of Ophtalmology, Centro Hospitalar de Entre o Douro e Vouga, Rua Dr. Cândido Pinho, Santa Maria da Feira
Portugal
Background and Objective: Optical coherence tomography (OCT) plays a crucial role in guiding the treatment and establishing the prognosis of diabetic macular edema (DME). We aimed to determine which OCT biomarkers respond better to intravitreal triamcinolone acetonide (IVTA) switch after antivascular endothelial growth factor (anti-VEGF) treatment poor response.
Materials and Methods: Fifty-eight eyes with DME, submitted to IVTA switch, were included in this retrospective study. OCT biomarkers and best-corrected visual acuity (VA) were assessed, before and after treatment with a mean follow-up of 2.9 months.
Results: IVTA switch resulted in improved VA, central foveal thickness (CFT), and macular volume. Intraretinal cysts decreased or disappeared completely (P = 0.007) in 84.2% of the eyes, as well as the hyperreflective foci (P = 0.004) and the subretinal fluid (P = 0.02).
Conclusion: We show that IVTA switch is an effective rescue therapy in anti-VEGF therapy refractory DME. OCT plays an important role in selecting the most appropriate treatment, namely between anti-VEGF and steroids.
How to cite this article:
Matias MJ, Miranda V, Aguiar CP, Duarte L. Optical coherence tomography biomarkers after intravitreal triamcinolone acetonide in patients with diabetic macular edema.Pan Am J Ophthalmol 2023;5:10-10
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How to cite this URL:
Matias MJ, Miranda V, Aguiar CP, Duarte L. Optical coherence tomography biomarkers after intravitreal triamcinolone acetonide in patients with diabetic macular edema. Pan Am J Ophthalmol [serial online] 2023 [cited 2023 Sep 22 ];5:10-10
Available from: https://www.thepajo.org/article.asp?issn=2666-4909;year=2023;volume=5;issue=1;spage=10;epage=10;aulast=Matias;type=0 |
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