The purpose is to report a case of horseshoe macular tear and its management. Case reports of a patient with blunt trauma including findings on clinical examination, color fundus photography, and spectral-domain optical coherence tomography (OCT). A 23-year-old presented with a blunt ocular trauma from a plastic toy in the right eye. Fundoscopy revealed a horseshoe macular tear associated with a partial posterior vitreous detachment (PVD). OCT confirmed a full thickness macular tear with radial extension and associated retinal thickening. The patient underwent conservative management and was followed closely showing a spontaneous resolution of the macular tear. Our case report describes an example of traumatic horseshoe macular tear; we hypothesized that the PVD and the secondary inflammation as a result of the trauma were responsible for the spontaneous resolution of macular tear in our case.

Background: Uveal melanoma (UM) is the most common primary intraocular tumor in adults. Despite successful local treatment, approximately 50% of these patients develop lethal metastatic disease. BRCA1-associated protein 1 (BAP1) encodes BAP1, which functions as a tumor suppressor. Inactivation by a somatic mutation in BAP1 results in a loss of protein expression, which is associated with increased risk of metastasis. Aim: To analyze the expression of BAP1 protein in primary uveal tumors and their corresponding metastasis in an animal model of UM and to determine whether BAP1 expression is lost during the metastatic process. Subjects and Methods: Postmortem eyes and lungs with metastasis from nine rabbits previously inoculated with human UM cells expressing BAP1 (92.1 strain) were analyzed. Immunohistochemistry was performed on formalin-fixed paraffin-embedded samples using a monoclonal BAP1 (C-4) antibody. Expression was evaluated by the extent and intensity of staining. All primary tumors and metastasis were positive for BAP1. Results: The staining was diffuse and intense in the primary tumors of four rabbits (67%), focal-intense in one rabbit and focal-mild in one rabbit. All lung metastasis showed focal staining. All animals with intense BAP1 staining in the primary tumor showed mild BAP1 in the metastasis. Discussion: A predominant pattern observed between primary and metastatic lesion shows a transition from moderate into mild intensity and diffuse into the focal extent, suggesting a decrease in BAP1 expression. Future studies, including the human tissue of primary UM and their corresponding metastasis, should be performed to corroborate these findings.

The objective is to report a case about corneal tattooing on leukoma in PUC Campinas Hospital. It is a retrospective case report, about 64-year-old patient with corneal opacity of the left eye without visual acuity. The patient was not satisfied with the esthetics of the leukoma and did not tolerate the use of a contact lens. For this reason, corneal tattooing with stromal micropuncture and pigment impregnation was indicated.