A case of bilateral ocular decompression retinopathy (ODR) is presented on a patient with steroid-induced glaucoma, after immediate postoperative period trabeculectomy with mitomycin C; we observed a sudden decrease of vision due to the presence of multiple superficial retinal hemorrhages that resolved completely 2 weeks after the postoperative period. ODR is a rare complication after glaucoma surgery. Although it has been described in the literature, this case shows an unusual presentation, bilateral and consecutive in a patient with steroid-induced glaucoma.

Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare inflammatory disorder affecting renal and ocular systems. Certain associations have been made with systemic conditions such as autoimmune diseases, infections, and even medications. We present the case of a 16-year-old male patient who presented to our service with bilateral uveitis and urinary symptoms, associated with proteinuria, glycosuria, increase in serum creatinine and beta-2 microglobulin in urine considering TINU as the main differential diagnosis. Antibiotics were considered a possible trigger in this patient. He presented an adequate response to systemic and topical steroids and systemic immunomodulators. Renal biopsy results reported interstitial tubulonephritis. TINU syndrome is a rare autoimmune condition, mainly seen in younger patients. Multiple triggers have been associated. Renal compromise usually resolves spontaneously with a relatively rare risk of incomplete recovery as well as uveal compromise. However, early diagnosis and multidisciplinary management is fundamental in these patients.

Design: Observational, descriptive, and retrospective. Participants: A total of 84 patients diagnosed with tumor and simulating lesions in the ophthalmology unit ot the Hospital Universitario San Ignacio between 2010 – 2020. Methods: All patients with a ICD10 code according to tumoral or inflammatory disease of the orbit at Hospital Universitario San Ignacio between January 2010 and December 2020 were included, and the diagnosis was confirmed with the clinical history. Pathology was classified according to the histopathological report or definitive diagnosis made with diagnostic tests/imaging. Additionally, the following data were obtained: age, sex, history, evolution time, lesion origin (primary, invasion, or metastasis), laterality, location in relation to the muscular cone, lesion size, symptoms, signs, presence of adenomegaly, extension, diagnostic approaches, histopathological diagnosis, intra/extrahospital treatment, and outcome. A virtual data collection format was developed for data collection, with subsequent descriptive analysis reporting percentages. Results: In adult patients (over 18 years old), 60 lesions were diagnosed. The most frequent tumor pathologies in this group correspond to squamous cell carcinoma of the eyelid with invasion into the orbit, 6 cases (18.75%), cavernous hemangioma, 4 (12.5%), lymphoid tumors, 4 (12.5%), schwannoma, 2 (6.25%), and pleomorphic adenocarcinoma, 2 (6.25%). The main simulating lesion in the adult population corresponds to thyroid orbitopathy, which is attributed to 33.3% of all tumor or non-tumor lesions. In patients under 18 years of age, 24 lesions were diagnosed. The most frequent pathologies in this group corresponded to retinoblastoma, 11 cases (45.8%), rhabdomyosarcoma, 5 (20.8%), and cavernous hemangioma, 2 (8.3%). In patients under 18 years of age, 54.1% of cases resulted in loss of the eyeball. Conclusion: During the period from January 2010 to December 2020, 84 orbital tumors and simulating lesions were diagnosed. The most frequent tumor lesion in adults corresponds to squamous cell carcinoma of the eyelid with invasion into the orbit, and in patients under 18 years of age, it corresponds to retinoblastoma. Greater secondary loss of the eyeball is documented in this latter population group, requiring enucleation or evisceration in 54.1% of cases.