| CASE REPORT |
|
| Year : 2023 | Volume
: 5
| Issue : 1 | Page : 27 |
|
|
Tubulointerstitial nephritis with uveitis in a young male patient
Juan Jose Castro-Barandica1, Daniela A Esmeral-Ordonez1, Karol Quintero-Lizcano1, Carlos Mario Rangel2
1 Autonomous University of Bucaramanga, Bucaramanga; Virgilio Galvis Ophthalmological Center; Ophthalmologic Foundation of Santander, Floridablanca, Santander, Colombia
2 Autonomous University of Bucaramanga, Bucaramanga; Virgilio Galvis Ophthalmological Center; Ophthalmologic Foundation of Santander, Floridablanca, Santander; Industrial University of Santander, Bucaramanga, Colombia
Correspondence Address:
Juan Jose Castro-Barandica
Centro Oftalmológico Virgilio Galvis, FOSCAL Internacional, Calle 157#20 – 94, Torre C, Consultorio 301, Cañaveral, Floridablanca, Santander
Colombia
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/pajo.pajo_34_23
|
|
|
Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare inflammatory disorder affecting renal and ocular systems. Certain associations have been made with systemic conditions such as autoimmune diseases, infections, and even medications. We present the case of a 16-year-old male patient who presented to our service with bilateral uveitis and urinary symptoms, associated with proteinuria, glycosuria, increase in serum creatinine and beta-2 microglobulin in urine considering TINU as the main differential diagnosis. Antibiotics were considered a possible trigger in this patient. He presented an adequate response to systemic and topical steroids and systemic immunomodulators. Renal biopsy results reported interstitial tubulonephritis. TINU syndrome is a rare autoimmune condition, mainly seen in younger patients. Multiple triggers have been associated. Renal compromise usually resolves spontaneously with a relatively rare risk of incomplete recovery as well as uveal compromise. However, early diagnosis and multidisciplinary management is fundamental in these patients.
|
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
