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Year : 2022  |  Volume : 4  |  Issue : 1  |  Page : 36

Granulomatosis with polyangiitis patient with retinitis as an initial manifestation

Department of Ophthalmology of Penido Burnier Institute . Campinas, 1Department of Ophthalmology, University of Sao Paulo, Sao Paulo, Brazil

Correspondence Address:
Valdez Melo Dos Anjos Filho
José Paulino Street, 159, Apartment 1007, Bosque, Campinas, São Paulo
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/pajo.pajo_33_22

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The German pathologist Friedrich Wegener described granulomatosis with polyangiitis (GPA), formerly known as Wegener's Granulomatosis, in 1936. Lesions are inflammatory, and typically include vasculitis, necrosis, and granulomatous changes. Ocular symptoms may be the first manifestation of this disease in 16%–58% of cases. The ocular manifestations of GPA occur in the most diverse ways. Delayed diagnosis can have serious consequences for patients' vision, as can the preservation of the globe, in addition to other systemic involvement, which can be rapidly progressive in some cases, leading to long-term disability or mortality.

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